職    稱

  講師

科研方向

  植物和病毒互作，抗病毒藥劑研究 

招生專業(yè)

  植物保護(hù)（植物病理學(xué)） 

聯(lián)系方式

  kaiqiang1991@sdau.edu.cn

個人簡介

郝凱強(qiáng)，男，漢族，山東省青州人，農(nóng)學(xué)博士。近年來，發(fā)表以Chemical Engineering Journal，Journal of Nanobiotechnology，International Journal of Molecular Sciences為代表的科技論文13余篇。

教學(xué)背景及工作經(jīng)歷

2024.03-至      今：山東農(nóng)業(yè)大學(xué)植物保護(hù)學(xué)院\講師

2019.09-2023.12：沈陽農(nóng)業(yè)大學(xué)\植物保護(hù)學(xué)院\植物病理學(xué)專業(yè)\博士

2015.09-2017.07：云南農(nóng)業(yè)大學(xué)\植物保護(hù)學(xué)院\農(nóng)藥專業(yè)\碩士

2010.09-2014.07：山東農(nóng)業(yè)大學(xué)\植物保護(hù)學(xué)院\植物保護(hù)學(xué)專業(yè)\學(xué)士

教學(xué)工作

主要承擔(dān)本科生《普通植物病理學(xué)》、《普通植物病理學(xué)實(shí)驗(yàn)》、《植物保護(hù)概論》。

研究方向

1. 玉米褪綠斑駁病毒和植物互作機(jī)制；

2. 新型抗病毒納米藥劑的創(chuàng)制和應(yīng)用。

科研項(xiàng)目

1. 國家自然科學(xué)基金青年基金項(xiàng)目：miR827調(diào)控的磷平衡在玉米抗甘蔗花葉病毒中的作用機(jī)制研究，資助年限：2019.1-2021.12，參與人；

2. 中國煙草總公司云南省公司科技計(jì)劃項(xiàng)目-重大項(xiàng)目，利用TOM2A基因創(chuàng)制K326抗病毒新品系，資助年限：2022.01-2024.12，參與人；

3. 山東省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目：玉米重大病害成災(zāi)機(jī)制及防控技術(shù)研究，資助年限：2023.01-2025.12，課題一參與人。

代表性科研成果

1. Kaiqiang Hao, Xinran Gao, Miaoren Yang, Zhiping Wang, Mengnan An, He Liu, Zihao Xia, and Yuanhua Wu. A nanomaterial for the delivery of dsRNA as a strategy to alleviate viral infections in maize. Chemical Engineering Journal 488:150923 (2024). doi.org/10.1016/j.cej.2024.150923 (SCI, IF=13.3，1區(qū))；

2. Kaiqiang Hao, Miaoren Yang, Yakun Cui, Zhiyuan Jiao, Xinran Gao, Zhichao Du, Zhiping Wang, Mengnan An, Zihao Xia, and Yuanhua Wu. Transcriptomic and functional analyses reveal the different roles of Vitamins C, E, and K in regulating viral infections in maize. International Journal of Molecular Sciences 24(9) (2023). doi.org/10.3390/ijms24098012 (SCI, IF=4.9，2區(qū))；

3. Jie Wang, Kaiqiang Hao, Fangfei Yu, Lili Shen, Fenglong Wang, Jinguang Yang, and Chenyu Su. Field application of nanoliposomes delivered quercetin by inhibiting specific hsp70 gene expression against plant virus disease. Journal of Nanobiotechnology 20: 1-16 (2022). doi.org/10.1186/s12951-021-01223-6 (SCI, IF=10.6，1區(qū))；

4. Kaiqiang Hao, Beisen Lin#, Fuzhao Nian#, Xi Gao, Zhong Wei, Gang Luo, Yachun Lu, Mingxian Lan, Jinguang Yang, and Guoxing Wu. RNA-seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph. Revista Argentina de Microbiologia 51(3):268-77 (2019). doi.org/10.1016/j.ram.2018.08.007 (SCI, IF=1.8，4區(qū))；

5. Xinran Gao, Kaiqiang Hao, Zhichao Du, Sijia Zhang, Zhiping Wang, Mengnan An, Zihao Xia, and Yuanhua Wu. Identification of ceRNA-vsiRNA-mRNA network for exploring the mechanism underlying pathogenesis of sugarcane mosaic virus in resistant and susceptible maize inbred lines. Phytopathology Research 5(1):60 (2023). doi.org/10.1186/s42483-023-00216-7 (SCI, IF=3.2，2區(qū))；

6. Xinran Gao, Kaiqiang Hao, Zhichao Du, Sijia Zhang, Jinxiu Guo, Jian Li, Zhiping Wang, Mengnan An, Zihao Xia, and Yuanhua Wu. Whole-transcriptome characterization and functional analysis of lncRNA-miRNA-mRNA regulatory networks responsive to sugarcane mosaic virus in maize resistant and susceptible inbred lines. International Journal of Biological Macromolecules 257:128685 (2024). doi.org/10.1016/j.ijbiomac.2023.128685 (SCI, IF=7.7，1區(qū))；

7. Yubing Jiao, Xiuxiang Zhao, Kaiqiang Hao, Xinran Gao, Dan Xing, Zhiping Wang, Mengnan An, Zihao Xia, and Yuanhua Wu. Characterization of small interfering RNAs derived from pepper mild mottle virus in infected pepper plants by high-throughput sequencing. Virus Research 307:198607 (2022). doi.org/10.1016/j.virusres.2021.198607 (SCI, IF=2.5，4區(qū))；

8. Hangjun Sun, Lili Shen, Yuanxia Qin, Xiaowei Liu, Kaiqiang Hao, Ying Li, Jie Wang, Jinguang Yang, and Fenglong Wang. CLC-Nt1 affects potato virus Y infection via regulation of endoplasmic reticulum luminal Ph. New Phytologist 220(2):539-52 (2018). doi.org/10.1111/nph.15310 (SCI, IF=8.3，1區(qū))；

9. Zihao Xia, Sijia Zhang, Huiyan Guo, Xinran Gao, Kaiqiang Hao, Xue Dong, Jinxiu Guo, Jian Li, Zhiping Wang, Mengnan An, Yuanhua Wu, and Xueping Zhou. N6-methyladenosine RNA modification regulates maize resistance to maize chlorotic mottle virus infection. Journal of Agricultural and Food Chemistry. (2024). https://doi.org/10.1021/acs.jafc.4c04832 (SCI, IF=5.7，1區(qū));

10. Xinran Gao, Yuan Chen, Xuecong Luo, Zhichao Du, Kaiqiang Hao, Mengnan An, Zihao Xia, and Yuanhua Wu. Recombinase polymerase amplification assay for simultaneous detection of maize chlorotic mottle virus and sugarcane mosaic virus in maize. ACS Omega 6(28):18008-13 (2021). doi.org/10.1021/acsomega.1c01767 (SCI, IF=3.7，3區(qū))；

11. Yuan Chen, Shiping Guo, Lianqiang Jiang, Fangfang Yan, Kaiqiang Hao, Zhiping Wang, Mengnan An, Zihao Xia, Fangfang Li, and Xueping Zhou. Molecular characterization and pathogenicity of a novel monopartite geminivirus infecting tobacco in China. Virology 110061 (2024). doi.org/10.1016/j.virol.2024.110061 (SCI, IF=3.7，3區(qū))；

12. Yuanxia Qin, Jie Wang, Fenglong Wang, Lili Shen, Haixiang Zhou, Hangjun Sun, Kaiqiang Hao, Liyun Song, Zhicheng Zhou, and Chaoqun Zhang. Purification and characterization of a secretory alkaline metalloprotease with highly potent antiviral activity from Serratia marcescens strain S3. Journal of Agricultural and Food Chemistry 67(11):3168-78 (2019). doi.org/10.1021/acs.jafc.8b06909 (SCI, IF=5.7，1區(qū))；

13. Liyun Song, Jie Wang, Haiyan Jia, Ali Kamran, Yuanxia Qin, Yingjie Liu, Kaiqiang Hao, Fei Han, Chaoqun Zhang, and Bin Li. Identification and functional characterization of NbMLP28, a novel MLP-like protein 28 enhancing potato virus Y resistance in Nicotiana benthamiana. BMC microbiology 20:1-14 (2020). doi.org/10.1186/s12866-020-01725-7 (SCI, IF=4，2區(qū))；

14.  實(shí)用新型專利：郝凱強(qiáng),蘭明先,吳國星,何霞紅,秦小萍，高熹.(2017-02-15).CN205946941U.