職    稱

 教授

科研方向

 納米農(nóng)藥負(fù)載體系設(shè)計及構(gòu)筑

招生專業(yè)

 植物保護(hù)（農(nóng)藥學(xué)）

聯(lián)系方式

 0538-8242611；libeixing@126.com

個人簡介

李北興，男，漢族，山東省濟(jì)寧市金鄉(xiāng)縣人，群眾，農(nóng)學(xué)博士。現(xiàn)為山東省高等學(xué)校“青創(chuàng)團(tuán)隊計劃”團(tuán)隊帶頭人，入選中國科協(xié)青年人才托舉工程，全國農(nóng)藥學(xué)科優(yōu)秀中青年科技工作者。擔(dān)任《山東農(nóng)業(yè)大學(xué)學(xué)報（自然科學(xué)版）》編委，《植物醫(yī)學(xué)》、《農(nóng)藥學(xué)學(xué)報》等期刊青年編委。兼任中國植物保護(hù)學(xué)會青年工作委員會委員。近年來，主持國家自然科學(xué)基金、國家重點研發(fā)計劃子課題、中國博士后科學(xué)基金、中央引導(dǎo)地方科技發(fā)展專項等項目12項。H指數(shù)21，他引1200余次，以通訊/第一作者在Advanced Functional Materials、ACS Nano、Chemical Engineering Journal等期刊發(fā)表論文29篇，其中SCI收錄23篇，7篇IF>8，4篇IF>10，單篇最高被引87次。主編農(nóng)業(yè)農(nóng)村部規(guī)劃教材1部。授權(quán)專利8件，1項轉(zhuǎn)化落地。研制系列載藥產(chǎn)品，推廣應(yīng)用800余萬畝，以首位獲山東省高等學(xué)校科學(xué)技術(shù)二等獎等獎勵。主持入選中國高等教育博覽會“校企合作 雙百計劃”典型案例。

教學(xué)背景及工作經(jīng)歷

2024.01-至      今：山東農(nóng)業(yè)大學(xué)植物保護(hù)學(xué)院\教授

2021.11-2023.12：山東農(nóng)業(yè)大學(xué)\植物保護(hù)學(xué)院\副教授（五級）

2019.09-2021.10：山東農(nóng)業(yè)大學(xué)\植物保護(hù)學(xué)院\副教授（七級）

2016.09-2019.06：山東農(nóng)業(yè)大學(xué)\農(nóng)藥學(xué)專業(yè)\博士

2015.07-2016.08：山東農(nóng)業(yè)大學(xué)\農(nóng)藥環(huán)境毒理研究中心\實驗員

2012.09-2015.06：山東農(nóng)業(yè)大學(xué)\農(nóng)藥學(xué)專業(yè)\碩士

2008.09-2012.07：山東農(nóng)業(yè)大學(xué)\制藥工程專業(yè)\學(xué)士

教學(xué)工作

主要承擔(dān)本科生科生《儀器分析》、《植物化學(xué)保護(hù)實驗1》、《農(nóng)藥制劑學(xué)實驗》，碩士研究生《現(xiàn)代農(nóng)藥研究技術(shù)》，博士研究生《農(nóng)藥應(yīng)用工藝學(xué)》等課程的教學(xué)。

副主編農(nóng)業(yè)農(nóng)村部規(guī)劃教材《農(nóng)藥學(xué)實驗技術(shù)與指導(dǎo)（第三版）》1部。

指導(dǎo)本科生獲得山東省SRT計劃項目，中國國際大學(xué)生創(chuàng)新大賽金獎等多項獎勵，獲“山東農(nóng)業(yè)大學(xué)創(chuàng)新創(chuàng)業(yè)導(dǎo)師”等榮譽稱號。

研究方向

1. 新型微納米農(nóng)藥負(fù)載體系設(shè)計及構(gòu)筑。

2. 農(nóng)藥高效精準(zhǔn)對靶沉積技術(shù)及調(diào)控。

科研項目

1. 中國科協(xié)青年人才托舉工程，2022.12-2024.12，30萬元，主持。

2. 國家自然科學(xué)基金青年項目，吡唑醚菌酯微粒二次分散結(jié)構(gòu)與施用藥效的關(guān)聯(lián)機制及調(diào)控，2021.01-2023.12，24萬元，主持。

3. 國家重點研發(fā)計劃子課題，設(shè)施蔬果根腐病綠色防控技術(shù)與產(chǎn)品研發(fā)，2023.12-2027.12，24.07萬元，主持。

4. 中國博士后科學(xué)基金項目，連接臂依賴的腐植酸基納米農(nóng)藥負(fù)載體系構(gòu)筑及調(diào)控機理研究，2023.11-，8萬元，主持。

5. 中央引導(dǎo)地方科技發(fā)展專項資金項目，枸杞蚜蟲、木虱的綠色防控關(guān)鍵技術(shù)研發(fā)與應(yīng)用，2022.11-2024.11，50萬元，主持。

6. 山東省高等學(xué)校青創(chuàng)科技支持計劃，生物基納米農(nóng)藥負(fù)載體系構(gòu)建及調(diào)控機制研究，2023.01-2025.12，30萬元，主持。

7. 山東省自然科學(xué)基金項目，微囊化負(fù)載降低高魚毒吡唑醚菌酯施用風(fēng)險的機制及調(diào)控研究，2021.01-2023.12，15萬元，主持。

8. 山東農(nóng)業(yè)大學(xué)科研啟動基金，農(nóng)藥靶界面行為與藥效的耦合機制及調(diào)控，50萬元，主持。

9. 山東濱農(nóng)科技有限公司，氟吡菌酰胺防治作物病害應(yīng)用技術(shù)，2021.12-2022.12，20萬元，主持。

10. 山東濱農(nóng)科技有限公司，不同劑型氟吡菌酰胺單劑及混劑開發(fā)，2023.01-2023.12，12萬元，主持。

代表性科研成果

1. Tong-fang Jing, Da-xia Zhang, Yao-zhong Zhang, Yan Jin, Xian-zheng Han, Wei Mu, Bei-xing Li*, Feng Liu*. Adsorption behaviour and mechanism of Avermectin-based pesticides in soil driven by H-bonds formed between the compounds and humus. Chemical Engineering Journal, 2023, 459, 141647.

2. Haichao Cao, Yue Chen, Zhigang Qian, Tingjie Huang, Nan Zou, Daxia Zhang, Wei Mu, Beixing Li*, Feng Liu*. Amphiphilicity-driven amall alcohols regulate the flexibility of pesticide-loaded microcapsules for better foliar adhesion and utilization. ACS Appl. Mater. Interfaces, 2023, 15, 21444-21456.

3. Aiping Wang, Yue Sun, Zhengyi Sun, Xiao Liu, Xin Yu, Ke Li, Xianxia Zhang, Yue Xu, Wei Mu, Beixing Li*. Modification of sedimentation and bioaccumulation behavior as an efficient strategy to modulate the toxicity of pyraclostrobin to zebrafish (Danio rerio). Environmental Pollution, 2023, 322, 121164.

4.Jiang Du, Chonglin Wang, Yukun Liu, Chaobin Xue, Jiacheng Ge, Guodong Si, Xianzheng Han, Feng Liu, Daxia Zhang*, Beixing Li*. One-pot construction of epoxy resin nanocarrier delivering abamectin and its efficacy on plant root-knot nematodes. Pest Management Science, 2023, 79, 3103-3113.

5. Y. Gao, J. Luo, Y. Sun, H. Zhang, D. Zhang, F. Liu, W. Mu*, B. Li*. Photosensitivity and a precise combination of size-dependent lambda-cyhalothrin microcapsules synergistically generate better insecticidal efficacy. Journal of Integrative Agriculture, 2023, 22(5): 1477-1488.

6. X. Huang, A. Wang, J. Luo, Y. Gao, L. Guan, P. Zhang, F. Liu, W. Mu, B. Li*. Lambda-cyhalothrin-loaded nanocapsules pose an unacceptable acute toxicological risk to zebrafish (Danio rerio) at the adult and larval stages but present an acceptable risk to embryos. J. Hazard. Mater., 2022, 422, 126853.

7. J. Luo, Y. Gao, Y. Liu, X. Huang, D. Zhang, H. Cao, T. Jing, F. Liu,* B. Li*. Self-assembled degradable nanogels provide foliar affinity and pinning for pesticide delivery by flexibility and adhesiveness adjustment. ACS Nano, 2021, 15, 14598?14609.

8. J. Luo, Y. Gao, Y. Liu, J. Du, D. Zhang, H. Cao, T. Jing, B. Li*, F. Liu*. Using a reactive emulsifier to construct simple and convenient nanocapsules loaded with lambda-cyhalothrin to achieve efficient foliar delivery and insecticidal synergies. Nanoscale, 2021, 13, 15647–15658.

9. H. Cao, D. Zhang, S. Liu, J. Luo, T. Jing, S. Pan, F. Liu, B. Li*, W. Mu*. Achieving win-win ecotoxicological safety and fungicidal activity of pyraclostrobin-loaded polyurea microcapsules by selecting proper polyamines. J. Agric. Food Chem., 2021, 69(7), 2099-2107.

10. X. Li, L. He, X. Pang, Y. Gao, Y. Liu, P. Zhang, G. Wei, W. Mu, B. Li*, F. Liu*. Tank-mixing adjuvants enhanced the efficacy of fludioxonil on cucumber anthracnose by ameliorating the penetration ability of active ingredients on target interface. Colloid. Surface. B, 2021, 204, 111804.

11. S. Pan, H. Cao, B. Li*, D. Zhang, W. Mu, F. Liu*. Improving the efficacy against crop foliage disease by regulating fungicide adhesion on leaves with soft microcapsules. Pest Manag. Sci., 2021, 77(10), 4418-4424.

12. X. Li, Y. Liu, L. He, Y. Gao, W. Mu, P. Zhang, B. Li,* F. Liu*. Fungicide formulations in?uence their control e?cacy by mediating physicochemical properties of spray dilutions and their interaction with target leaves. J. Agric. Food Chem., 2020, 68(5), 1198-1206.

13. B. Li, Y. Liu, P. Zhang, X. Li, X. Pang, Y. Zhao, H. Li, F. Liu, J. Lin, W. Mu?. Selection of organosilicone surfactants for tank-mixed pesticides considering the balance between synergistic effects on pests and environmental risks. Chemosphere, 2019, 217, 591-598.

14. Y. Gao, X. Li, L. He, B. Li,* W. Mu, F. Liu*. Role of adjuvants in the management of anthracnose change in the crystal morphology and wetting properties of fungicides. J. Agric. Food Chem., 2019, 67, 9232?9240.

15. B. Li,# Y. Ren,# D. Zhang, S. Xu, W. Mu, F. Liu*. Modifying the formulation of abamectin to promote its efficacy on southern root-knot nematode (Meloidogyne incognita) under blending-of-soil and root-irrigation conditions. J. Agric. Food Chem., 2018, 66, 799?805.

16. B. Li,# J. Lin,# X. Pang,# H. Li, X. Li, F. Liu, W. Mu*. Binary mixtures of alcohol ethoxylates, nonylphenol ethoxylates and pesticides exhibit comparative bioactivity against three pests and toxicological risks to aquatic organisms. Chemosphere, 2018, 204, 44-50.

17. B. Li, X. Li, Y. Liu, D. Zhang, J. Lin, W. Mu, F. Liu*. Easily tunable membrane thickness of microcapsules by using a coordination assembly on the liquid-liquid interface. Front. Chem., 2018, 6, 387.

18. B. Li,# X. Pang,# P. Zhang,# J. Lin, X. Li, Y. Liu, H. Li, F. Liu, W. Mu*. Alcohol ethoxylates significantly synergize pesticides than alkylphenol ethoxylates considering bioactivity against three pests and joint toxicity to Daphnia magna. Sci. Total Environ., 2018, 644, 1452-1459.

19. B. Li,# H. Li,# X. Pang,# K. Cui, J. Lin, F. Liu, W. Mu*. Quaternary ammonium cationic surfactants increase bioactivity of indoxacarb on pests and toxicological risk to Daphnia magna. Ecotoxicol. Environ. Safety, 2018, 149, 190-196.

20. B. Li,# W. Wang,# X. Zhang, D. Zhang, Y. Ren, Y. Gao, W. Mu, F. Liu*. Using coordination assembly as the microencapsulation strategy to promote the efficacy and environmental safety of pyraclostrobin. Adv. Funct. Mater., 2017, 27(29), 1701841.

21. B. Li,# W. Wang,# X. Zhang, D. Zhang, W. Mu, F. Liu*. Integrating uniform design and response surface methodology to optimize thiacloprid suspension. Sci. Rep., 2017, 7, 46018.