一、個(gè)人簡介

崔海濤，男，漢族，山東省菏澤市鄄城人，中共黨員，遺傳學(xué)博士，“閩江學(xué)者”。中國植物病理學(xué)會(huì)理事，中國熱帶作物學(xué)會(huì)青年工作委員會(huì)委員。2010年10月到2016年12月，德國馬普植物育種研究所博士后。2017年2月至2023年8月，福建農(nóng)林大學(xué)海峽聯(lián)合研究院植物免疫中心副主任，作物遺傳育種與綜合利用教育部重點(diǎn)實(shí)驗(yàn)室副主任。近年來，主持國家自然科學(xué)基金面上項(xiàng)目2項(xiàng)，主持福建省自然基金重點(diǎn)項(xiàng)目等省部級(jí)項(xiàng)目4項(xiàng)。發(fā)表以《Molecular Plant》為代表的科技論文20余篇。

二、研究方向：

1. 植物的抗病分子機(jī)理研究。以模式植物擬南芥，和作物水稻為研究對(duì)象，深入研究重要免疫調(diào)控蛋白EDS1/PAD4的生化和分子機(jī)制；位于細(xì)胞膜上的成孔蛋白在調(diào)控植物免疫中的作用機(jī)制；研究和挖掘新的抗性基因，研究其分子作用機(jī)理，揭示植物免疫領(lǐng)域的前沿科學(xué)問題。

2. 水稻與稻瘟病菌的互作機(jī)制研究。稻瘟病是水稻生產(chǎn)上的首要病害，我們通過轉(zhuǎn)錄組學(xué)，蛋白組學(xué)，和反向遺傳學(xué)，得到了一些調(diào)控水稻抗稻瘟病的新基因，通過過分子生物學(xué)，細(xì)胞生物學(xué)和生物化學(xué)等手段，深入研究水稻與稻瘟病菌互作的分子機(jī)制。

3. 鐮刀真菌的致病機(jī)理研究。鐮刀菌是引起很多作物重要病害的病原真菌，比如小麥莖腐病、玉米莖腐病和香蕉枯萎病等。我們通過比較基因組，現(xiàn)代轉(zhuǎn)錄組和分子生化技術(shù)，深入研究鐮刀菌的毒性分子機(jī)制，與寄主互作的分子機(jī)制，為防治鐮刀真菌病害和作物抗病育種提供理論依據(jù)和新策略。

三、主持和參加科研項(xiàng)目

（1）國家自然科學(xué)基金委員會(huì)，面上項(xiàng)目，31970281，2020-2023，在研，主持

（2）國家自然科學(xué)基金委員會(huì)，面上項(xiàng)目，31770277，2018-2021，結(jié)題，主持

（3）福建省自然基金重點(diǎn)項(xiàng)目，2023J02011, 2023-2026,在研，主持

（4）福建省自然基金面上項(xiàng)目，2018J01609，2018-2021，結(jié)題，主持

（5）中央引導(dǎo)地方科技發(fā)展資金專項(xiàng)（廣西），2021ZYZX1037，2022-2024，在研，合作方負(fù)責(zé)人

（6）中德科學(xué)中心，中德合作交流項(xiàng)目，M-0275，2021-2024，在研，主要參加人

（7）福建省“閩江學(xué)者”獎(jiǎng)勵(lì)計(jì)劃，2018-2022，主持

四、發(fā)表論文

第一作者或通訊作者論文

1. Zeng, Y., Zheng, Z., Hessler, G., Zou, K., Leng, J., Bautor, J., Stuttmann, J., Xue, L., Parker, J.E., and Cui, H. (2023). Arabidopsis PAD4 promotes the maturation and nuclear accumulation of immune-related cysteine protease RD19. J Exp Bot. 10.1093/jxb/erad454. (IF=8)

2. Zhong, Z., Zhong, L., Zhu, X., Jiang, Y., Zheng, Y., Lan, T., and Cui, H. (2023). Transcription factor OsSPL10 interacts with OsJAmyb to regulate blast resistance in rice. The Crop Journal. 10.1016/j.cj.2023.10.015 (IF = 6.5)

3. Yu, D., Dong, X., Zou, K., Jiang, X.D., Sun, Y.B., Min, Z., Zhang, L.P., Cui, H., and Hu, J.Y. (2023). A hidden mutation in the seventh WD40-repeat of COP1 determines the early flowering trait in a set of Arabidopsis myc mutants. The Plant cell 35, 345-350. (IF = 12) (共同通訊)

4. Parker, J.E., Hessler, G., and Cui, H. (2022). A new biochemistry connecting pathogen detection to induced defense in plants. New Phytol. （IF = 10.32）

5. Ling, H., Fu, X., Huang, N., Zhong, Z., Su, W., Lin, W., Cui, H., and Que, Y. (2022). A sugarcane smut fungus effector simulates the host endogenous elicitor peptide to suppress plant immunity. New Phytol 233, 919-933. （IF = 10.32）

6. Zhao, C., Li, S., Du, C., Gao, H., Yang, D., Fu, G., and Cui, H. (2022). Establishment of a Protoplasts-Based Transient Expression System in Banana (Musa spp.). Agronomy 12, 2648

7. Yang, D., Li, S., Xiao, Y., Lu, L., Zheng, Z., Tang, D., and Cui, H. (2021). Transcriptome analysis of rice response to blast fungus identified core genes involved in immunity. Plant Cell Environ 44, 3103-3121. （IF = 7.9）

8. Zhao, C., Tang, Y., Wang, J., Zeng, Y., Sun, H., Zheng, Z., Su, R., Schneeberger, K., Parker, J.E., and Cui, H. (2021). A mis-regulated cyclic nucleotide-gated channel mediates cytosolic calcium elevation and activates immunity in Arabidopsis. New Phytol 230, 1078-1094. （IF = 10.32）

9. Leng, J., Tu, W., Hou, Y., and Cui, H. (2021). Temperature-Inducible Transgenic EDS1 and PAD4 in Arabidopsis Confer an Enhanced Disease Resistance at Elevated Temperature. Plants 10, 1258. （IF = 4.6）

10. Cui, H., J. Qiu, Y. Zhou, D. D. Bhandari, C. Zhao, J. Bautor and J. E. Parker (2018). Antagonism of Transcription Factor MYC2 by EDS1/PAD4 Complexes Bolsters Salicylic Acid Defense in Arabidopsis Effector-Triggered Immunity. Mol Plant 11(8): 1053-1066. （IF = 21.9）

11. Cui, H., Gobbato, E., Kracher, B., Qiu, J., Bautor, J., and Parker, J.E. (2017). A core function of EDS1 with PAD4 is to protect the salicylic acid defense sector in Arabidopsis immunity. New Phytol 213, 1802-1817. （IF = 10.32）

12. Cui, H., Tsuda, K., and Parker, J.E. (2015). Effector-triggered immunity: from pathogen perception to robust defense. Annual review of plant biology 66, 487-511. (IF = 28.3）

13. Cui, H., Y. Wang, L. Xue, J. Chu, C. Yan, J. Fu, M. Chen, R. W. Innes and J. M. Zhou (2010). Pseudomonas syringae effector protein AvrB perturbs Arabidopsis hormone signaling by activating MAP kinase 4. Cell Host Microbe 7(2): 164-175. (IF = 31.3）

14. Cui, H., T. Xiang and J. M. Zhou (2009). Plant immunity: a lesson from pathogenic bacterial effector proteins. Cell Microbiol 11(10): 1453-1461. (IF = 4.1）

15. Shang, Y., X. Li, H. Cui, P. He, R. Thilmony, S. Chintamanani, J. Zwiesler-Vollick, S. Gopalan, X. Tang and J. M. Zhou (2006). RAR1, a central player in plant immunity, is targeted by Pseudomonas syringae effector AvrB. Proc Natl Acad Sci U S A 103(50): 19200-19205. (共一作) (IF = 12.77)

共同作者論文：

1. Zhuo, T., Wang, X., Chen, Z., Cui, H., Zeng, Y., Chen, Y., Fan, X., Hu, X., and Zou, H. (2020). The Ralstonia solanacearum effector RipI induces a defence reaction by interacting with the bHLH93 transcription factor in Nicotiana benthamiana. Mol Plant Pathol 21, 999-1004.

2. Zhou, Y., Tergemina, E., Cui, H., Forderer, A., Hartwig, B., Velikkakam James, G., Schneeberger, K., and Turck, F. (2017). Ctf4-related protein recruits LHP1-PRC2 to maintain H3K27me3 levels in dividing cells in Arabidopsis thaliana. Proc Natl Acad Sci U S A 114, 4833-4838.

3. Mei, S., Hou, S., Cui, H., Feng, F., and Rong, W. (2016). Characterization of the interaction between Oidium heveae and Arabidopsis thaliana. Mol Plant Pathol 17, 1331-1343.

4. Xue, L., H, Cui., B. Buer, V. Vijayakumar, P. M. Delaux, S. Junkermann and M. Bucher (2015). Network of GRAS Transcription Factors Involved in the Control of Arbuscule Development in Lotus japonicus. Plant Physiol 167(3): 854-871.

5. Zhang, J., H. Lu, X. Li, Y. Li, H. Cui, C. K. Wen, X. Tang, Z. Su and J. M. Zhou (2010). Effector-triggered and pathogen-associated molecular pattern-triggered immunity differentially contribute to basal resistance to Pseudomonas syringae. Mol Plant Microbe Interact 23(7): 940-948

6. Chen, H., L. Xue, S. Chintamanani, H. Germain, H. Lin, H. Cui, R. Cai, J. Zuo, X. Tang, X. Li, H. Guo and J. M. Zhou (2009). ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 repress SALICYLIC ACID INDUCTION DEFICIENT2 expression to negatively regulate plant innate immunity in Arabidopsis. The Plant Cell 21(8): 2527-2540.

7. Zhang, J., F. Shao, Y. Li, H. Cui, L. Chen, H. Li, Y. Zou, C. Long, L. Lan, J. Chai, S. Chen, X. Tang and J. M. Zhou (2007). A Pseudomonas syringae effector inactivates MAPKs to suppress PAMP-induced immunity in plants. Cell Host Microbe 1(3): 175-185.、

五、聯(lián)系方式：

電子郵箱：E-mail: haitao.cui@hotmail.com